|The PAX6 pax6 (Catalog #MBS9200327) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PAX6 Antibody (Ascites) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. MyBioSource\'s PAX6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunofluorescence (IF).
IF~~1:10~50. Researchers should empirically determine the suitability of the PAX6 pax6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PAX6 pax6 product has the following accession number(s) (GI #4505615) (NCBI Accession #NP_000271.1) (Uniprot Accession #P26367). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PAX6 Antibody (Ascites) with the following immunoassay(s):
Western Blot (WB) (PAX6 western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PAX6 antibody detected the PAX6 protein (arrow).)
Immunofluorescence (IF) (Confocal immunofluorescent analysis of PAX6 Antibody (Ascites) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).)
This gene encodes paired box gene 6, one of many human
homologs of the Drosophila melanogaster gene prd. In addition to
the hallmark feature of this gene family, a conserved paired box
domain, the encoded protein also contains a homeo box domain. Both
domains are known to bind DNA, and function as regulators of gene
transcription. This gene is expressed in the developing nervous
system, and in developing eyes. Mutations in this gene are known to
cause ocular disorders such as aniridia and Peter\'s anomaly.
Alternatively spliced transcript variants encoding either the same
or different isoform have been found for this gene. [provided by
Antigen Type: Recombinant Protein. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PAX6 are readily searchable from our website. Different antibodies against the same target such as PAX6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Aniridia, Brain Diseases, Coloboma, Congenital Abnormalities, Craniofacial Abnormalities, Intellectual Disability, Necrosis, Nervous System Diseases, Nervous System Malformations, Peters anomaly are some of the diseases may be linked to PAX6 Antibody (Ascites).