anti-PAX8 antibody product blog
Tags: Antibody; Monoclonal Antibody; PAX8; anti-PAX8 antibody;
The PAX8 pax8 (Catalog #MBS2540225) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PAX8 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PAX8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).WB: 1:200-1:2000
IHC: 1:20-1:200. Researchers should empirically determine the suitability of the PAX8 pax8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PAX8 pax8 product has the following accession number(s) (GI #5803117) (NCBI Accession #NP_003457.1) (Uniprot Accession #Q06710). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PAX8 Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of SKOV-3 cells using PAX8-Specific Monoclonal Antibody at dilution of 1:500)
PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells. Mutation of PAX8 will cause congenital hypothyroidism non-goitrous type 2 (CHNG2). This antibody is specific to Pax8. It will not cross react with other PAX members.
Immunogen: Synthetic Peptide. Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PAX8 are readily searchable from our website. Different antibodies against the same target such as PAX8 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Death, Hyperplasia, Kidney Diseases, Liver Neoplasms, Lung Diseases, Necrosis, Neoplasm Metastasis, Neoplasms, Experimental, Thyroid Diseases, Thyroid cancer, follicular are some of the diseases may be linked to PAX8 Monoclonal Antibody. PAX8 also interacts with the following gene(s): BCL2, FOXI1, NKX2-1, PARP1, PPARG, WNT9B, WT1. Bladder, Brain, Cervix, Eye, Kidney, Lung, Lymph Node, Ovary, Pancreas, Thyroid tissues are correlated with this protein.