|The PDCD4 pdcd4 (Catalog #MBS2540227) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PDCD4 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PDCD4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB).
Western Blot: 1:1000-1:10000
Immunohistochemistry: 1:20-1:200. Researchers should empirically determine the suitability of the PDCD4 pdcd4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PDCD4 pdcd4 product has the following accession number(s) (GI #21735596) (NCBI Accession #NP_055271.2) (Uniprot Accession #Q53EL6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PDCD4 Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (HeLa cells were subjected to SDS PAGE followed by western blot with PDCD4 antibody at dilution of 1:4000)
Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation, progression and invasion. It was first identified as being differnetially upregulated during apoptosis. Pdcd4 interferes with the activity of the eukaryotic initiation factor (eIF) 4A by displacing the scaffold protein eIF4G from its binding to the RNA helicase eIF4A.
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Immunogen: PDCD4 fusion protein ag19239. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PDCD4 are readily searchable from our website. Different antibodies against the same target such as PDCD4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. PDCD4 also interacts with the following gene(s): BTRC, EIF4A1, EIF4G1, MYB, RPS13, RPS6KA1. Blood, Bone, Brain, Heart, Liver, Lung, Lymph, Lymph Node, Muscle, Skin tissues are correlated with this protein. Adenocarcinoma, Breast Neoplasms, Cell Transformation, Neoplastic, Inflammation, Liver Diseases, Liver Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasm Invasiveness, Neoplasm Metastasis are some of the diseases may be linked to PDCD4 Monoclonal Antibody.