anti-PDE1B antibody product blog
Tags: Antibody; Monoclonal Antibody; PDE1B; anti-PDE1B antibody;
The PDE1B pde1b (Catalog #MBS834004) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s PDE1B can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB).FC: 1:100
IF: 1:100
WB: 1:2000. Researchers should empirically determine the suitability of the PDE1B pde1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PDE1B pde1b product has the following accession number(s) (GI #35192996) (NCBI Accession #AAH58531.1) (Uniprot Accession #Q01065). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PDE1B antibody with the following immunoassay(s):
Flow Cytometry (FC/FACS) (Flow Cytometric analysis of HEK293T cells transfected with either recombinant PDE1B protein (red) or empty vector (blue) stained using PDE1B antibody)
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PDE1B protein (Right) or empty vector (Left) detected with PDE1B antibody)
Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant PDE1B protein using PDE1B antibody)
Mouse monoclonal PDE1B antibody.
Biological Significance: Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex. Cross-Reactivity: Human, Dog, Rat, Monkey
Immunogen: PDE1B antibody was raised in Mouse using full length human recombinant protein of human PDE1B produced in HEK293T cell as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PDE1B are readily searchable from our website. Different antibodies against the same target such as PDE1B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Embryonic Tissue, Eye, Heart, Liver, Lung, Ovary, Spinal Cord, Testis tissues are correlated with this protein. The following patways have been known to be associated with this gene. Brain Diseases, Cardiovascular Diseases, Cognition Disorders, Disease Models, Animal, Fever, Hypertension, Inflammation, Mental Disorders, Neoplasm Metastasis, Nervous System Diseases are some of the diseases may be linked to PDE1B antibody.