anti-PDYN antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-PDYN antibody; PDYN;
The PDYN pdyn (Catalog #MBS649095) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PDYN (Proenkephalin-B, Beta-neoendorphin-dynorphin, Preprodynorphin, MGC26418) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PDYN can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP).Suitable for use in ELISA, Western Blot and Immunoprecipitation. Researchers should empirically determine the suitability of the PDYN pdyn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PDYN pdyn product has the following accession number(s) (GI #300116234) (NCBI Accession #NP_001177829.1) (Uniprot Accession #P01213). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
KRYGGFLRRI RPKLKWDNQK RYGGFLRRQF KVVTRSQEDP NAYSGELFDA.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PDYN (Proenkephalin-B, Beta-neoendorphin-dynorphin, Preprodynorphin, MGC26418) with the following immunoassay(s):
Western Blot (WB) (Western Blot detection against Immunogen (31.24kD).)
Western Blot (WB) (Western Blot analysis of PDYN expression in transfected 293T cell line by PDYN monoclonal antibody.)
Immunoprecipitation (IP) (Immunoprecipitation of PDYN transfected lysate using PDYN monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with PDYN rabbit polyclonal antibody)
Testing Data (Detection limit for recombinant GST tagged PDYN is 0.1ng/ml as a capture antibody.)
Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin. Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
Immunogen: Partial recombinant corresponding to aa205-255 from human PDYN (NP_077722) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PDYN are readily searchable from our website. Different antibodies against the same target such as PDYN may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. PDYN also interacts with the following gene(s): NPY, OPRK1, OPRL1, OPRM1, PNOC, POMC.