anti-PEG10 antibody product blog
Tags: Antibody; Monoclonal Antibody; PEG10; anti-PEG10 antibody;
The PEG10 n/a (Catalog #MBS6011513) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PEG10 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PEG10 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).Western Bloting: 1:500-1:2000., Immunohistochemistry: 1:200-1:1000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the PEG10 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PEG10 n/a product has the following accession number(s) (GI #285014444) (NCBI Accession #ADC33128.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
PEG10, paternally expressed 10. The PEG10 includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frameshifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.
Immunogen: Purified recombinant fragment of human PEG10 expressed in E. coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PEG10 are readily searchable from our website. Different antibodies against the same target such as PEG10 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.