|The PEX6 pex6 (Catalog #MBS802684) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PEX6 Antibody: ATTO 488 reacts with Human, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s PEX6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC).
1:1000 WB. Researchers should empirically determine the suitability of the PEX6 pex6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PEX6 pex6 product has the following accession number(s) (GI #194018488) (NCBI Accession #NP_000278.3) (Uniprot Accession #Q13608). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PEX6 Antibody: ATTO 488 with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Rat Brain showing detection of ~100 kDa PEX6 protein using Mouse Anti-PEX6 Monoclonal Antibody, Clone S233-8. Lane 1: Molecular Weight Ladder. Lane 2: Rat Brain. Load: 15 ug. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-PEX6 Monoclonal Antibody at 1:200 for 16 hours at 4 degree C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:1000 for 1 hour RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~100 kDa.)
Background Info: Detects a 100 kDa protein corresponding to the molecular weight of PEX6
Scientific Background: This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases. This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity. Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6.
Conjugate: ATTO 488. Storage Buffer: PBS pH 7.4, 50% glycerol, 0.1% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PEX6 are readily searchable from our website. Different antibodies against the same target such as PEX6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. PEX6 also interacts with the following gene(s): PEX1, PEX10, PEX12, PEX13, PEX14, PEX26, PEX3, PEX5, PEX7. The following patways have been known to be associated with this gene.