anti-PGRPL antibody product blog
Tags: Antibody; Monoclonal Antibody; PGRPL; anti-PGRPL antibody;
The PGRPL n/a (Catalog #MBS832670) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s PGRPL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB: 1:2000. Researchers should empirically determine the suitability of the PGRPL n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PGRPL antibody with the following immunoassay(s):
Western Blot (WB) ()
Mouse monoclonal PGRPL antibody.
Biological Significance: Peptidoglycan recognition proteins (PGRPs) are pattern recognition molecules that recognize bacteria and their unique cell wall component, peptidoglycan (PGN). Mammals have four PGRPs, designated in humans PGRP-S(24kDa), PGRPL(60~65kDa), PGRP-Ia(38kDa), and PGRPIbeta(44kDa). Human PGRPs are differentially expressed in various tissues and organs: PGRP-S mainly in the bone marrow and Polymorphonuclear leukocyte (PMNs), PGRP-L mainly in the liver, and PGRP-Ia and PGRP-Ib mainly in the esophagus. The function of only one mammalian PGRP, PGRP-S, is currently known. Mouse PGRP-S is present in neutrophils and inhibits growth of Gram-positive bacteria and, therefore, may function as a neutrophil antibacterial protein. Cross-Reactivity: Human
Immunogen: PGRPL antibody was raised in Mouse using Peptidoglycan recognition protein(PGrP)-L purified form Human protein as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PGRPL are readily searchable from our website. Different antibodies against the same target such as PGRPL may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.