anti-Phospho-Tau antibody product blog
Tags: Antibody; PHOSPHO-TAU; Monoclonal Antibody; anti-Phospho-Tau antibody;
The Tau n/a (Catalog #MBS588135) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Phospho-Tau (tyr 18) Mouse Monoclonal Antibody (9G3) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Tau can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).If reconstituted in 100 muL: WB: 1:1000-1:5000; IHC: 1:1000-1:5000; IF: 1:2000-1:5000. Researchers should empirically determine the suitability of the Tau n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Phospho-Tau (tyr 18) Mouse Monoclonal Antibody (9G3) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of transfeeted HeLa cell slysates: 1: Tau 2: Tau.+ Fyn 3: Tau + Src 4: non-transfeeted 5: TauY18F 6: TauY18F + Fyn 7: TauY18F + Src)
Immunofluorescence (IF) (Immunofluorescence analysis of transfected HeLa cells stained with the antiphospho- Tau (Tyr 18) antibody, dilution 1:200: A: Tau; B: Tau + Fyn)
Tauopathies are a group of diverse dementias and movement disorders which have a common pathological feature in that they all display the presence of intracellular accumulation of abnormal filaments of Tau protein. While the abnormal phosphorylation of Tau on serine and threonine has been well established in the disease process, its phosphorylation on tyrosine 18 has only recently been described as present in Alzheimer\'s disease (AD) brain.
Immunogen: Peptide. Preservative: None. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Tau are readily searchable from our website. Different antibodies against the same target such as Tau may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.