anti-PI3K p85 antibody product blog
Tags: Antibody; Monoclonal Antibody; PI3K p85; anti-PI3K p85 antibody;
The PI3K p85(alpha) pik3r1 (Catalog #MBS2540230) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PI 3 kinase p85 alpha Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s PI 3 kinase p85 alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA).WB: 1:1000-1:10000
IHC: 1:20-1:200
IF: 1:50-1:500. Researchers should empirically determine the suitability of the PI3K p85(alpha) pik3r1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PI3K p85(alpha) pik3r1 product has the following accession number(s) (GI #335057534) (NCBI Accession #NP_001229395.1) (Uniprot Accession #P27986). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PI 3 kinase p85 alpha Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of fetal Human brain tissue using PI3K p85(alpha) Monoclonal Antibody at dilution of 1:4000)
Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer, which is composed of a P110 catalytic subunit and a P85 regulatory subunit, is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.
Immunogen: Fusion protein of PI3K p85(alpha). Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PI3K p85(alpha) are readily searchable from our website. Different antibodies against the same target such as PI3K p85(alpha) may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. PI3K p85(alpha) also interacts with the following gene(s): AKT1, CTNNB1, EGFR, IGF1R, INSR, IRS1, PDGFRA, PIK3CA, PIK3CB, SRC. The following patways have been known to be associated with this gene.