|The PKHD1 hps1 (Catalog #MBS476819) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-PKHD1 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PKHD1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the PKHD1 hps1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PKHD1 hps1 product has the following accession number(s) (GI #21239258) (NCBI Accession #AAM44232.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Entrez Summary: Mutations in the PKHD1 gene, which encodes fibrocystin, cause autosomal recessive polycystic kidney disease (ARPKD). Unfortunately, the lack of specific antibodies to the mouse protein impairs the study of splicing, post-translational processing, shedding, and temporal and spatial expression of endogenous fibrocystin at the cellular and subcellular level.
Immunogen: Purified recombinant fragment of HPS1 expressed in E Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PKHD1 are readily searchable from our website. Different antibodies against the same target such as PKHD1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Abnormalities, Drug-Induced, Brain Diseases, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Heart Diseases, Hemorrhage, Inflammation, Mental Disorders, Nervous System Diseases are some of the diseases may be linked to Anti-PKHD1 Mouse mAb. Blood, Bone, Bone Marrow, Brain, Embryonic Tissue, Eye, Heart, Lung, Nerve, Skin tissues are correlated with this protein. The following patways have been known to be associated with this gene. PKHD1 also interacts with the following gene(s): AP3B1, BLOC1S2, BLOC1S3, BLOC1S4, BLOC1S6, DTNBP1, HPS3, HPS4, HPS5, HPS6.