|The PLAA plaa (Catalog #MBS649979) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PLAA (Phospholipase A-2-activating Protein, PLA2P, PLAP, FLJ11281, FLJ12699) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PLAA can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the PLAA plaa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PLAA plaa product has the following accession number(s) (GI #72534670) (NCBI Accession #NP_001026859.1) (Uniprot Accession #Q9Y263). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
KNIHIALATL ALNYSVCFHK DHNIEGKAQC LSLISTILEV VQDLEATFRL LVALGTLISD DSNAVQLAKS LGVDSQIKKY SSVSEPAKVS ECCRFILNLL.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
PLAA stimulates human neutrophil aggregation and release of lysosomal enzymes, superoxide, and eicosanoids. It plays an important role in the regulation of specific inflammatory processes connected to such diseases as inflammatory bowel disease, pancreatitis, rheumatoid arthritis, and cutaneous malignant melanoma.
Immunogen: Partial recombinant corresponding to aa639-738 from PLaa (NP_004244) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PLAA are readily searchable from our website. Different antibodies against the same target such as PLAA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Disease Models, Animal, Drug-Induced Liver Injury, Inflammation, Kidney Diseases, Liver Diseases, Lung Diseases, Necrosis, Nervous System Diseases, Neurotoxicity Syndromes, Poisoning are some of the diseases may be linked to PLAA (Phospholipase A-2-activating Protein, PLA2P, PLAP, FLJ11281, FLJ12699). Adipose Tissue, Blood, Bone, Brain, Connective Tissue, Kidney, Liver, Lung, Muscle, Vascular tissues are correlated with this protein. PLAA also interacts with the following gene(s): CAV1, PDIA3, VCP. The following patways have been known to be associated with this gene.