anti-PLEC antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-PLEC antibody; PLEC; PLEC1;
The PLEC plec (Catalog #MBS642981) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PLEC1 (Plectin, PCN, PLTN, Hemidesmosomal Protein 1, HD1, Plectin-1, PLEC) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PLEC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the PLEC plec for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PLEC plec product has the following accession number(s) (GI #47607492) (NCBI Accession #NP_000436.2) (Uniprot Accession #Q15149). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV PLDEALQRGT VDARTAQKLR DVGAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PLEC1 (Plectin, PCN, PLTN, Hemidesmosomal Protein 1, HD1, Plectin-1, PLEC) with the following immunoassay(s):
Western Blot (WB) (Western Blot detection against Immunogen (37.84kD).)
Testing Data (Detection limit for recombinant GST tagged PLEC1 is ~0.3ng/ml as a capture antibody.)
Plectin is a 500kD ubiquitously expressed intermediate filament binding protein and member of the plakin family, which acts as a link between intermediate filaments (IF), microtubules and actin microfilaments within the cytoskeleton, and between the cytoskeleton and plasma membranes connecting different cells, thereby maintaining tissue integrity.
Immunogen: Partial recombinant corresponding to aa4384-4494 from human PLEC1 (NP_000436) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PLEC are readily searchable from our website. Different antibodies against the same target such as PLEC may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Cardiovascular Diseases, Epidermolysis Bullosa Simplex With Pyloric Atresia, Heart Diseases, Immune System Diseases, Kidney Diseases, Liver Diseases, Liver Neoplasms, Neoplasms, Nervous System Diseases are some of the diseases may be linked to PLEC1 (Plectin, PCN, PLTN, Hemidesmosomal Protein 1, HD1, Plectin-1, PLEC). The following patways have been known to be associated with this gene.