anti-Proto-oncogene c-Src; pp60c-src antibody product blog
Tags: Antibody; Monoclonal Antibody; SRC; anti-Proto-oncogene c-Src; pp60c-src antibody; Proto-oncogene c-Src; pp60c-src;
The Proto-oncogene c-Src; pp60c-src src (Catalog #MBS565087) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Src monoclonal antibody (5A18) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Src can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) (PS), Western Blot (WB).Western Blot (1ug/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Detects a band of ~60kDa by Western blot. Researchers should empirically determine the suitability of the Proto-oncogene c-Src; pp60c-src src for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Proto-oncogene c-Src; pp60c-src src product has the following accession number(s) (GI #125711) (NCBI Accession #P12931.3) (Uniprot Accession #P12931). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Src monoclonal antibody (5A18) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of Src using 20µg of whole cell lysate (Lane 2=HeLa, Lane 3=3T3, Lane 4=PC12) probed with with Src, mAb (5A18) at 1µg/ml.)
Src is a member of the tyrosine kinase family that was originally identified as the oncogene of Rous sarcoma virus. The catalytic domain contains a tyrosine autophosphorylation site that increases kinase activity when phosphorylated. The Src family of tyrosine kinase is involved in a variety of receptor-induced signal transduction pathways such as immune recognition rec.
Immunogen: Recombinant human full length c-Src. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Proto-oncogene c-Src; pp60c-src are readily searchable from our website. Different antibodies against the same target such as Proto-oncogene c-Src; pp60c-src may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Brain, Embryonic Tissue, Kidney, Liver, Lung, Muscle, Nerve, Prostate tissues are correlated with this protein. The following patways have been known to be associated with this gene. Proto-oncogene c-Src; pp60c-src also interacts with the following gene(s): BCAR1, CBL, CRK, EGFR, ESR1, KHDRBS1, PTK2, PTPN1, PXN, STAT3. Breast Neoplasms, Cell Transformation, Neoplastic, Disease Models, Animal, Inflammation, Lung Neoplasms, Necrosis, Neoplasm Invasiveness, Neoplasm Metastasis, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to Src monoclonal antibody (5A18).