anti-PSMB4 antibody product blog
Tags: Antibody; Monoclonal Antibody; PSMB4; anti-PSMB4 antibody;
The PSMB4 psmb4 (Catalog #MBS838160) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s PSMB4 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Western Blot (WB).FC: 1:100
WB: 1:500. Researchers should empirically determine the suitability of the PSMB4 psmb4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PSMB4 psmb4 product has the following accession number(s) (GI #22538467) (NCBI Accession #NP_002787.2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PSMB4 antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PSMB4 protein (Right) or empty vector (Left) detected with PSMB4 antibody)
Mouse monoclonal PSMB4 antibody.
Biological Significance: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB4 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Cross-Reactivity: Human
Immunogen: PSMB4 antibody was raised in mouse using a full length recombinant protein of human PSMB4 (NP_002787) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PSMB4 are readily searchable from our website. Different antibodies against the same target such as PSMB4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adenocarcinoma, Carcinoma, Carcinoma, Hepatocellular, Cardiovascular Diseases, Cell Transformation, Neoplastic, Heart Diseases, Hypertrophy, Inflammation, Liver Diseases, Liver Neoplasms are some of the diseases may be linked to PSMB4 antibody. Blood, Bone, Heart, Intestine, Kidney, Liver, Muscle, Placenta, Prostate, Stomach tissues are correlated with this protein. The following patways have been known to be associated with this gene.