anti-PSME1 antibody product blog
Tags: Antibody; Monoclonal Antibody; PSME1; anti-PSME1 antibody;
The PSME1 psme1 (Catalog #MBS200337) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PSME1 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PSME1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the PSME1 psme1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The PSME1 psme1 product has the following accession number(s) (GI #5453990) (NCBI Accession #NP_006254) (Uniprot Accession #Q06323). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PSME1 antibody with the following immunoassay(s):
Western Blot (WB) (The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PSME1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1. : HeLa cell lysate Lane 2. : LNCap cell lysate Lane 3. : A549 cell lysate Lane 4. : 293T cell lysate Lane 5. : Jurkat cell lysate Lane 6. : Raji cell lysate Lane 7. : A431 cell lysate)
PSME1, also known as PA28 alpha, is an interferon gamma (IFNG) inducible proteasome activator required for presentation of certain major histocompatibility (MHC) class I antigens. The PSME1 complex is an alternative proteasome activator that does not employ the use of ubiquitin. The PSME1 complex is composed of two homologous subunits, alpha and beta, which have similar catalytic properties and associate to form a hexameric ring.
Antigen Species: Human
Immunogen: Recombinant human PSME1 (1-249aa) purified from E. coli. Clone Note: Anti-human PSME1 mAb, clone AT12H3, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PSME1 protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PSME1 are readily searchable from our website. Different antibodies against the same target such as PSME1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. PSME1 also interacts with the following gene(s): PSMB10, PSMB2, PSMB8, PSMB9, PSME2. Brain Diseases, Carcinoma, Carcinoma, Hepatocellular, Cardiovascular Diseases, Inflammation, Liver Diseases, Liver Neoplasms, Necrosis, Nervous System Diseases, Ovarian Diseases are some of the diseases may be linked to PSME1 antibody.