|The PTGS2 ptgs2 (Catalog #MBS9133035) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTGS2 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PTGS2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:1000 - 1:2000. Researchers should empirically determine the suitability of the PTGS2 ptgs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PTGS2 ptgs2 product has the following accession number(s) (GI #4506265) (NCBI Accession #NP_000954.1) (Uniprot Accession #P35354). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
Immunogen: A synthetic peptide of human PTGS2
Immunogen Species: Human. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Peripheral membrane protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PTGS2 are readily searchable from our website. Different antibodies against the same target such as PTGS2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Intestine, Kidney, Liver, Lung, Muscle, Stomach, Vascular tissues are correlated with this protein. Adenocarcinoma, Carcinoma, Colonic Neoplasms, Colorectal Neoplasms, Drug Toxicity, Inflammation, Lung Diseases, Neoplasms, Nervous System Diseases, Skin Diseases are some of the diseases may be linked to PTGS2 Monoclonal Antibody. PTGS2 also interacts with the following gene(s): CAV1, TP53, ZFP36.