anti-pxo1_110 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-pxo1_110 antibody; pxo1_110; Anthrax Protective Antigen;
The pxo1_110 paga (Catalog #MBS565142) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anthrax Protective Antigen monoclonal antibody (PA6) reacts with Bacillus anthracis and may cross-react with other species as described in the data sheet. MyBioSource\'s Anthrax Protective Antigen can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the pxo1_110 paga for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The pxo1_110 paga product has the following accession number(s) (GI #17380160) (NCBI Accession #P13423.2) (Uniprot Accession #P13423). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The exotoxin produced by B. anthracis is composed of three proteins: a cell-receptor binding protein known as Protective Antigen (PA), and two enzymes, Edema Factor (EF) and Lethal Factor (LF). An 83 kDa form of PA binds to a cell surface receptor and, upon proteolytic activation to a 63 kDa fragment, heptamerizes to form a membrane channel that mediates the entry of three molecules of LF or EF into the cells. PA and LF form Lethal Toxin, which is the dominant virulence factor produced by B. Anthracis and is the major cause of death in infected animals.
Immunogen: Anthrax protective antigen
Source: Purified from hybridoma tissue culture supernatant. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing pxo1_110 are readily searchable from our website. Different antibodies against the same target such as pxo1_110 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.