anti-QPRT antibody product blog
Tags: Antibody; Monoclonal Antibody; QPRT; anti-QPRT antibody;
The QPRT qprt (Catalog #MBS832964) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s QPRT can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Western Blot (WB).FC: 1:100
IHC: 1:150
WB: 1:2000. Researchers should empirically determine the suitability of the QPRT qprt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The QPRT qprt product has the following accession number(s) (GI #45269149) (NCBI Accession #NP_055113) (Uniprot Accession #Q15274). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the QPRT antibody with the following immunoassay(s):
Flow Cytometry (FC/FACS) (Flow Cytometric analysis of HEK293T cells transfected with either recombinant QPRT protein (red) or empty vector (blue) stained using QPRT antibody)
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant QPRT protein (Right) or empty vector (Left) detected with QPRT antibody)
Immunohistochemistry (IHC) (Immunohistochemical analysis of QPRT protein in paraffin embedded Human liver tissue using QPRT antibody)
Mouse monoclonal QPRT antibody.
Biological Significance: QPRT is a key enzyme in catabolism of quinolin ate, an intermediate in the tryptophan-nicotin amide adeninedinucleotide pathway. Quinolin ate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer\'s disease, and Huntington\'s disease. Cross-Reactivity: Human
Immunogen: QPRT antibody was raised in mouse using a full length recombinant protein of human QPRT (NP_055113) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing QPRT are readily searchable from our website. Different antibodies against the same target such as QPRT may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Carcinoma, Cell Transformation, Neoplastic, Chromosome Aberrations, Cognition Disorders, Inflammation, Kidney Diseases, Nervous System Diseases are some of the diseases may be linked to QPRT antibody. Blood, Brain, Kidney, Liver tissues are correlated with this protein.