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anti-RB1-S807 antibody product blog

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Posted on 2017-06-03 09:04:22 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; RB1-S807; anti-RB1-S807 antibody;
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The RB1-S807 rb1 (Catalog #MBS9132867) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospho-RB1-S807 Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s RB1-S807 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200. Researchers should empirically determine the suitability of the RB1-S807 rb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The RB1-S807 rb1 product has the following accession number(s) (GI #132164) (NCBI Accession #P06400.2) (Uniprot Accession #P06400). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Phospho-RB1-S807 Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of A549 cells, using Phospho-RB1-S807 antibody.|Immunohistochemistry of paraffin-embedded mouse spleen using Phospho-RB1-S807 antibody at dilution of 1:100 (40x lens).|Immunohistochemistry of paraffin-embedded human mammary cancer using Phospho-RB1-S807 antibody at dilution of 1:100 (40x lens).|Immunohistochemistry of paraffin-embedded human tonsil using Phospho-RB1-S807 antibody at dilution of 1:100 (40x lens).|Immunohistochemistry of paraffin-embedded human colon carcinoma using Phospho-RB1-S807 antibody at dilution of 1:100 (40x lens).|Immunohistochemistry of paraffin-embedded human spleen using Phospho-RB1-S807 antibody at dilution of 1:100 (40x lens).|Immunohistochemistry of paraffin-embedded mouse colon using Phospho-RB1-S807 antibody at dilution of 1:100 (40x lens).|Immunofluorescence analysis of MCF-7 cell using Phospho-RB1-S807 antibody.|Immunofluorescence analysis of CRC cell using Phospho-RB1-S807 antibody.|Immunofluorescence analysis of A549 cell using Phospho-RB1-S807 antibody.)
Western Blot (WB) RB1-S807.

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

Immunogen: A phospho specific peptide corresponding to residues surrounding S807 of human RB1. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing RB1-S807 are readily searchable from our website. Different antibodies against the same target such as RB1-S807 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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