anti-RFXAP antibody product blog
Tags: Antibody; Monoclonal Antibody; RFXAP; anti-RFXAP antibody;
The RFXAP rfxap (Catalog #MBS643820) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The RFXAP (Regulatory Factor X Associated Protein, Regulatory Factor X-associated Protein, RFX-associated Protein, RFX DNA-binding Complex 36kD Subunit) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s RFXAP can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA).Suitable for use in ELISA. Researchers should empirically determine the suitability of the RFXAP rfxap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The RFXAP rfxap product has the following accession number(s) (GI #4506501) (NCBI Accession #NP_000529.1) (Uniprot Accession #O00287). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
SDQALNCGGT ASTGSAGNVK LEESADNILS IVKQRTGSFG DRPARPTLLE QVLNQKRLSL LRSPEV*.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the RFXAP (Regulatory Factor X Associated Protein, Regulatory Factor X-associated Protein, RFX-associated Protein, RFX DNA-binding Complex 36kD Subunit) with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of RFXAP expression in transfected 293T cell line by RFXAP monoclonal antibody.|Lane 1: RFXAP transfected lysate (Predicted MW: 28.3kD).|Lane 2: Non-transfected lysate.)
Testing Data (Detection limit for recombinant GST tagged RFXAP is ~3ng/ml as a capture antibody.)
Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene.
Immunogen: Partial recombinant corresponding to aa179-245, from human RFXAP (NP_000529) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing RFXAP are readily searchable from our website. Different antibodies against the same target such as RFXAP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.