|The ROR2 ror2 (Catalog #MBS476710) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-ROR2 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ROR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the ROR2 ror2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ROR2 ror2 product has the following accession number(s) (GI #11228721) (NCBI Accession #AAG33132.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Entrez Summary: The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.
Immunogen: Purified recombinant fragment of MYL2 expressed in E Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ROR2 are readily searchable from our website. Different antibodies against the same target such as ROR2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. ROR2 also interacts with the following gene(s): FZD2, FZD5, MAGED1, WNT5A. Bone, Brain, Connective Tissue, Embryonic Tissue, Eye, Heart, Kidney, Liver, Lung, Stomach tissues are correlated with this protein. The following patways have been known to be associated with this gene. BRACHYDACTYLY, TYPE B1, Bone Diseases, Developmental, Carcinoma, Congenital Abnormalities, Craniofacial Abnormalities, Eye Abnormalities, Liver Neoplasms, Lung Neoplasms, Nervous System Malformations, Robinow syndrome, autosomal recessive are some of the diseases may be linked to Anti-ROR2 Mouse mAb.