|The RPTOR rptor (Catalog #MBS476489) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-RPTOR Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s RPTOR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the RPTOR rptor for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The RPTOR rptor product has the following accession number(s) (GI #958990067) (NCBI Accession #JAP00440.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Entrez Summary: This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen: Purified recombinant fragment of human RPTOR (AA: 874-1009) expressed in E Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing RPTOR are readily searchable from our website. Different antibodies against the same target such as RPTOR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. RPTOR also interacts with the following gene(s): AKT1S1, EIF4EBP1, MLST8, MTOR, RHEB, RPS6KB1, RRAGA, RRAGB, RRAGC, RRAGD. Blood, Bone, Brain, Connective Tissue, Kidney, Liver, Lung, Muscle, Nerve, Prostate tissues are correlated with this protein. Breast Neoplasms, Carcinoma, Fatty Liver, Heart Diseases, Hyperplasia, Hypertrophy, Inflammation, Insulin Resistance, Kidney Diseases, Prostatic Neoplasms are some of the diseases may be linked to Anti-RPTOR Mouse mAb.