anti-RPTP rho antibody product blog
Tags: Antibody; Monoclonal Antibody; RPTP rho; anti-RPTP rho antibody;
The RPTP rho n/a (Catalog #MBS833510) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s RPTP rho can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP).WB: 1:5000
IP: 2 ul. Researchers should empirically determine the suitability of the RPTP rho n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the RPTP rho antibody with the following immunoassay(s):
Western Blot (WB) ()
Mouse monoclonal RPTP rho antibody.
Biological Significance: RPTP rho is a transmembrane protein that is highly expressed in the developing and adult central nervous system. It is a member of the RPTP R2B subfamily, which includes PTPK, PTPu and PCP-2. The R2B phosphatases are known to interact with members of the cadherin/catenin complex. These four RPTPs share the same domain structure: an extracelluar domain, a juxtamembrane region, and two phosphatase domains. The extracellular domain of PTPR mediates cell-cell aggregation and that mutational inactivation of this phosphatase could promote tumor migration and metastasis. PTPRT is the most frequently mutated PTP in human cancers. STAT3 is a substrate of PTPRT. Cross-Reactivity: Human
Immunogen: RPTP rho antibody was raised in Mouse using a recombinant human protein purified from E Coli as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing RPTP rho are readily searchable from our website. Different antibodies against the same target such as RPTP rho may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.