|The S100A8/MRP8 s100a8 (Catalog #MBS2400517) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-S100A8/MRP8 Antibody (clone MAC 387, Azide-free) reacts with Human
Predicted: Mouse, Dog, Guinea pig, Rat, Pig, Cat, Monkey and may cross-react with other species as described in the data sheet. MyBioSource\'s S100A8/MRP8 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin.
IHC-P: 5 ug/ml. Researchers should empirically determine the suitability of the S100A8/MRP8 s100a8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The S100A8/MRP8 s100a8 product has the following accession number(s) (GI #21614544) (NCBI Accession #NP_002955.2) (Uniprot Accession #P05109). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-S100A8/MRP8 Antibody (clone MAC 387, Azide-free) with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-S100A8 antibody IHC of human liver, hepatocytes and macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.)
S100A8 is a calcium- and zinc-binding protein which plays a prominentrole in the regulation of inflammatory processes and immune response. Itcan induce neutrophil chemotaxis and adhesion. Predominantly found ascalprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions.
Immunogen: Affinity purified monocyte membrane preparation.
Conjugation: Azide-free Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing S100A8/MRP8 are readily searchable from our website. Different antibodies against the same target such as S100A8/MRP8 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Breast Neoplasms, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Heart Diseases, Inflammation, Kidney Diseases, Lung Neoplasms, Necrosis, Nervous System Diseases are some of the diseases may be linked to Anti-S100A8/MRP8 Antibody (clone MAC 387, Azide-free). Blood, Bone, Bone Marrow, Brain, Kidney, Liver, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. S100A8/MRP8 also interacts with the following gene(s): CSF3, LY96, MNDA, MYD88, S100A12, S100A9, TIRAP, TLR4.