anti-SCN3A antibody product blog
Tags: Antibody; Monoclonal Antibody; Scn3a; anti-SCN3A antibody;
The SCN3A scn3a (Catalog #MBS6005508) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SCN3A (Sodium Channel Protein Type 3 Subunit alpha, Sodium Channel Protein Brain III Subunit alpha, Sodium Channel Protein Type III Subunit alpha, Voltage-gated Sodium Channel Subtype III, Voltage-gated Sodium Channel Subunit alpha Nav1.3, KIAA1356, NAC3) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s SCN3A can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the SCN3A scn3a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SCN3A scn3a product has the following accession number(s) (GI #126362955) (NCBI Accession #NP_001075146.1) (Uniprot Accession #Q9NY46). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
LCESGEMDAL RIQMEDRFMA SNPSKVSYEP ITTTLKRKQE EVSAAIIQRN FRCYLLKQRL KNISSNYNKE AIKGRIDLPI KQDMIIDKLN GNSTPEKTDG *.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the SCN3A (Sodium Channel Protein Type 3 Subunit alpha, Sodium Channel Protein Brain III Subunit alpha, Sodium Channel Protein Type III Subunit alpha, Voltage-gated Sodium Channel Subtype III, Voltage-gated Sodium Channel Subunit alpha Nav1.3, KIAA1356, NAC3) with the following immunoassay(s):
Western Blot (WB) (Western Blot detection against Immunogen (37.11kD).)
Testing Data (Detection limit for recombinant GST tagged SCN3A is ~0.3ng/ml as a capture antibody.)
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.
Immunogen: Partial recombinant corresponding to aa1861-1961 from human SCN3A (NP_008853) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SCN3A are readily searchable from our website. Different antibodies against the same target such as SCN3A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.