anti-Serpin A3 antibody product blog
Tags: Antibody; Monoclonal Antibody; Serpin A3; anti-Serpin A3 antibody;
The Serpin A3 serpina3 (Catalog #MBS690887) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human Serpin A3 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Serpin A3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Serpin A3 serpina3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The Serpin A3 serpina3 product has the following accession number(s) (GI #50659080) (NCBI Accession #NP_001076.2) (Uniprot Accession #P01011). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.
Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with recombinant human Serpin-A3. Reconstitution: Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Serpin A3 are readily searchable from our website. Different antibodies against the same target such as Serpin A3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Liver, Lung, Uterus tissues are correlated with this protein. Cardiovascular Diseases, Heart Failure, Hypertension, Inflammation, Liver Diseases, Mental Disorders, Necrosis, Neoplasms, Seizures are some of the diseases may be linked to Mouse Anti-Human Serpin A3. The following patways have been known to be associated with this gene.