anti-SIM2 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-Sim2 antibody; Sim2;
The SIM2 sim2 (Catalog #MBS606461) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SIM2 (Single-minded Homolog 2, Class E Basic Helix-loop-helix Protein 15, bHLHe15, BHLHE15) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s SIM2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the SIM2 sim2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SIM2 sim2 product has the following accession number(s) (GI #4827004) (NCBI Accession #NP_005060.1) (Uniprot Accession #Q14190). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the SIM2 (Single-minded Homolog 2, Class E Basic Helix-loop-helix Protein 15, bHLHe15, BHLHE15) with the following immunoassay(s):
Western Blot (WB) (Western blot detection of GST tagged recombinant human Single-minded homolog 2. Note the GST tag alone is 26kD.)
ELISA (EIA) (Sandwich ELISA using mouse monoclonal antibody to human Single-minded homolog 2 as a capture antibody. The detection limit for recombinant GST tagged Single-minded homolog 2 is 0.03ng/ml.)
Single-minded homolog 2 is a transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tisues expressed during development. Efficient DNA binding requires dimerisation with another bHLH protein. It forms a heterodimer with ARNT.
Immunogen: Partial recombinant human Single-minded homolog 2 (aa426-526) with a GST tag. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SIM2 are readily searchable from our website. Different antibodies against the same target such as SIM2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Breast Neoplasms, Cleft Palate, Craniofacial Abnormalities, Inflammation, Obesity are some of the diseases may be linked to SIM2 (Single-minded Homolog 2, Class E Basic Helix-loop-helix Protein 15, bHLHe15, BHLHE15). SIM2 also interacts with the following gene(s): ARNT, EPO. Bone, Brain, Kidney, Lung, Prostate, Testis tissues are correlated with this protein.