anti-SLC11A1 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-Slc11a1 antibody; Slc11a1;
The SLC11A1 slc11a1 (Catalog #MBS6004701) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SLC11A1 (Natural Resistance-associated Macrophage Protein 1, NRAMP 1, LSH, NRAMP, NRAMP1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s SLC11A1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the SLC11A1 slc11a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SLC11A1 slc11a1 product has the following accession number(s) (GI #49256585) (NCBI Accession #NM_000578) (Uniprot Accession #P49279). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
QAFYQKTNQA AFNICANSSL HDYAKIFPMN NATVAVDIYQ GGV.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the SLC11A1 (Natural Resistance-associated Macrophage Protein 1, NRAMP 1, LSH, NRAMP, NRAMP1) with the following immunoassay(s):
Western Blot (WB) (Western Blot detection against Immunogen (30.84kD).)
Western Blot (WB) (Western Blot analysis of MBS6004701 expression in human liver.)
Testing Data (Detection limit for recombinant GST tagged SLC11A1 is ~0.03ng/ml as a capture antibody.)
NRAMP1, also known as SLC11A1, is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as leprosy and tuberculosis, and inflammatory diseases such as Crohn disease and rheumatoid arthritis. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
Immunogen: Partial recombinant corresponding to aa308-351 from human SLC11A1 (NP_000569) with GST tag. MW of the GST tag alone is 26kD. Grade: Affinity Purified. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SLC11A1 are readily searchable from our website. Different antibodies against the same target such as SLC11A1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.