|The SLC2A2 slc2a2 (Catalog #MBS9133036) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC2A2 Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s SLC2A2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:1000 - 1:2000. Researchers should empirically determine the suitability of the SLC2A2 slc2a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SLC2A2 slc2a2 product has the following accession number(s) (GI #4557851) (NCBI Accession #NP_000331.1) (Uniprot Accession #P11168). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene.
Immunogen: A synthetic peptide of human SLC2A2
Immunogen Species: Human. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location: Membrane, Multi-pass membrane protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SLC2A2 are readily searchable from our website. Different antibodies against the same target such as SLC2A2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. SLC2A2 also interacts with the following gene(s): FOXA2, GCG, GCK, HNF1A, IGF1R, INSR, PDX1, SLC2A5, SLC5A1. The following patways have been known to be associated with this gene. Heart, Kidney, Liver, Lung, Muscle tissues are correlated with this protein. Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 2, Fanconi Syndrome, Glucose Intolerance, Hepatomegaly, Hyperglycemia, Inflammation, Insulin Resistance, Kidney Diseases, Liver Diseases are some of the diseases may be linked to SLC2A2 Monoclonal Antibody.