anti-SMARCE1 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-SMARCE1 antibody; SMARCE1; BAF57;
The SMARCE1 smarce1 (Catalog #MBS6000654) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The BAF57 (SWI/SNF-related Matrix-associated Actin-dependent Regulator of Chromatin Subfamily E Member 1, BRG1-associated Factor 57, SMARCE1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s BAF57 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP).Suitable for use in ELISA, Western Blot and Immunoprecipitation.
Other applications not tested. Researchers should empirically determine the suitability of the SMARCE1 smarce1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SMARCE1 smarce1 product has the following accession number(s) (GI #2914753) (NCBI Accession #NM_003079) (Uniprot Accession #Q969G3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
RYSRKVWDQV KASNPDLKLW EIGKIIGGMW RDLTDEEKQE YLNEYEAEKI EYNESMKAYH NSPAYLAY.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the BAF57 (SWI/SNF-related Matrix-associated Actin-dependent Regulator of Chromatin Subfamily E Member 1, BRG1-associated Factor 57, SMARCE1) with the following immunoassay(s):
Western Blot (WB) (Western Blot detection against Immunogen (33.59kD) using MBS6000654.)
Immunoprecipitation (IP) (Immunoprecipitation of SMARCE1 transfected lysate using MBS6000654 and Protein A Magnetic Bead and immunoblotted with SMARCE1 rabbit polyclonal antibody.)
SMARCE1/BAF57 protein is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. SMARCE1/BAF57 can bind to 4-way junction DNA (which is thought to mimic the topology of DNA as it enters or exits the nucleosome), either alone or when in the SWI/SNF complex.
Immunogen: Partial recombinant corresponding to aa75-143 from human SMARCE1 (NP_003070) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SMARCE1 are readily searchable from our website. Different antibodies against the same target such as SMARCE1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Heart, Lymph, Lymph Node, Mammary Gland, Muscle, Ovary, Prostate, Testis, Vascular tissues are correlated with this protein.