anti-SMC-1 antibody product blog
Tags: Antibody; Monoclonal Antibody; SMC-1; anti-SMC-1 antibody;
The SMC-1 smc1a (Catalog #MBS395178) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SMC-1 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s SMC-1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). Researchers should empirically determine the suitability of the SMC-1 smc1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The SMC-1 smc1a product has the following accession number(s) (GI #30581135) (NCBI Accession #NP_006297.2) (Uniprot Accession #Q14683). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the SMC-1 with the following immunoassay(s):
Western Blot/Blotting (Western blotting using)
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromosome proteins are conserved in eukaryotes lead to mitotic chromosome segregation defects, suggesting a critical function of SMC family proteins in mitotic chromosome dynamics.
Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant protein corresponding to amino acids 402-894 of human SMC1 and mouse myeloma cells. Positive Control: HeLa cells. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SMC-1 are readily searchable from our website. Different antibodies against the same target such as SMC-1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Cardiomyopathies, CdLS, X-Linked, Death, Heart Diseases, Hypertrophy, Immune System Diseases, Neoplasms, Precancerous Conditions are some of the diseases may be linked to SMC-1. The following patways have been known to be associated with this gene. Blood, Bone, Bone Marrow, Embryonic Tissue, Esophagus, Eye, Heart, Lung, Mouth, Muscle tissues are correlated with this protein. SMC-1 also interacts with the following gene(s): ATM, RAD21, SMC3, STAG2, STAG3.