anti-Sox-2 antibody product blog
Tags: Antibody; Monoclonal Antibody; SOX-2; anti-SOX-2 antibody;
The Sox-2 sox2 (Catalog #MBS840023) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Sox-2 Antibody (Clone # 57CT23.3.4) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Sox-2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF).Western blot: ~1:200 - 1:2000, IHC: 1:50 - 1:100, FACS: 1:10 - 1:50, IF: 1:100. Researchers should empirically determine the suitability of the Sox-2 sox2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Sox-2 sox2 product has the following accession number(s) (GI #854182) (NCBI Accession #CAA83435.1) (Uniprot Accession #P48431). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Sox-2 Antibody (Clone # 57CT23.3.4) with the following immunoassay(s):
Testing Data
Monoclonal Antibody to detect Sox-2 in human samples.
Background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes clusters at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
Immunogen: SOX2 recombinant protein is used to produce this monoclonal antibody.
Positive Control: Western blot: SOX-2 protein, IHC: human lung carcinoma, FACS: NCI-H460 cells, IF: A549 and SY5S cells. Handling: The antibody solution should be gently mixed before use. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Sox-2 are readily searchable from our website. Different antibodies against the same target such as Sox-2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Ear, Embryonic Tissue, Eye, Lung, Mouth, Muscle, Pituitary Gland, Placenta, Testis tissues are correlated with this protein.