Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Monoclonal Antibody Blog  rightarrow anti-SPARC  antibody  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
 • anti-MCM2 antibody blog
 • anti-Buprenorphine antibody blog
 • anti-HIV reverse transcriptase (HIV-RT) antibody blog
 • anti-CD144 antibody blog
 • anti-Dengue Virus (DENV-pan NS1) antibody blog
 • anti-mTOR/Tor antibody blog
 • anti-ARRB1 antibody blog
 • anti-Grin2b antibody blog
 • anti-CRP antibody blog
 • anti-RV1734 antibody blog
 • anti-IL20RB antibody blog
 • anti-FKBP5 antibody blog
 • anti-Scn8a antibody blog
 • anti-Phosphatase, Alkaline, Intestine antibody blog
 • anti-GCG antibody blog
 • anti-CD34 Class I antibody blog
 • anti-Flag antibody blog
 • anti-HSPA8 antibody blog
 • anti-MHC Class I antibody blog
 • anti-NCK1 antibody blog
Blog Categories separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
Our Best Sellers moreseparator
 • POC1B Antibody
 • Probable ATP-dependent RNA helicase DDX58 (DDX58) ELISA Kit
 • Caspase 3, Active-Cleaved (CASP3) Antibody
 • CD8 Antibody
 • TNNT2 Antibody
 • Anti-thyroid-globulin antibody, ATGA ELISA Kit
 • Orexin A (OX-A) ELISA Kit
 • Osteopontin, OPN ELISA Kit
 • BMP-3A Antibody
 • AIM (CD5L) Antibody
 • RNF180 Antibody
 • Glyoxylate-hydroxypyruvate reductase A (ghrA) Recombinant Protein
 downarrow more ...

anti-SPARC  antibody product blog

Posted on 2017-03-03 22:10:08 by mybiosource_staff
Share it on ...     
Tags: Antibody; Monoclonal Antibody; SPARC ; anti-SPARC  antibody;
The SPARC  sparc (Catalog #MBS2544117) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human SPARC  Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s SPARC  can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA).
ELISA: 0.1-0.2 mug/mL. This antibody can be used at 0.1-0.2 mug/mL with the appropriate secondary reagents to detect Human SPARC. The detection limit for Human SPARC is approximately 0.00975 ng/well. Researchers should empirically determine the suitability of the SPARC  sparc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The SPARC  sparc product has the following accession number(s) (GI #4507171). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Secreted protein acidic and rich in cysteine (SPARC), also known as Osteonectin (ON), is a member of the SPARC family. SPARC consists of three domains: an EF-hand domain, a follistatin-like domain and a Kazal-like domain, and each of which has independent activity and unique properties. The activity of SPARC is context- and cell-type-dependent, which is highlighted by the fact that SPARC has shown seemingly contradictory effects on tumor progression in both clinical correlative studies and in animal models. The location of SPARC in the nuclear matrix of certain proliferating cells, but only in the cytosol of postmitotic neurons, indicates potential functions of SPARC as a nuclear protein, which might be involved in the regulation of cell cycle progression and mitosis. It functions not only to modulate cell-cell and cell-matrix interactions, but its de-adhesive and growth inhibitory properties in non-transformed cells have led to studies to assess its role in cancer. Its divergent actions reflect the complexity of this protein, because in certain types of cancers, such as melanomas and gliomas, SPARC is associated with a highly aggressive tumor phenotype, while in others, mainly ovarian, neuroblastomas and colorectal cancers, SPARC may function as a tumor suppressor. Recent studies have also demonstrated a role for SPARC in sensitizing therapy-resistant cancers. Notably, SPARC is linked to human obesity.

SPARC  sparc

Immunogen: Recombinant Human SPARC protein
Buffer: 0.2 mum filtered solution in PBS with 5% trehalose. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SPARC  are readily searchable from our website. Different antibodies against the same target such as SPARC  may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions