anti-SPR antibody product blog
Tags: Antibody; Monoclonal Antibody; SPR; anti-SPR antibody;
The SPR spr (Catalog #MBS834721) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s SPR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).WB: 1:500-2000. Researchers should empirically determine the suitability of the SPR spr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SPR spr product has the following accession number(s) (GI #4507185) (NCBI Accession #NP_003115) (Uniprot Accession #P35270). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the SPR antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant SPR protein (Right) or empty vector (Left) detected with SPR antibody)
Mouse monoclonal SPR antibody.
Biological Significance: This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystoniadue to sepiaterin reductase deficiency. Cross-Reactivity: Human, Monkey
Immunogen: SPR antibody was raised in mouse using a full length recombinant protein of human SPR (NP_003115) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SPR are readily searchable from our website. Different antibodies against the same target such as SPR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. SPR also interacts with the following gene(s): DHFR, GCH1, MCEE, PTS, QDPR. Brain Diseases, Carcinoma, Disease Models, Animal, Inflammation, Kidney Diseases, Liver Diseases, Necrosis, Neoplasms, Experimental, Nervous System Diseases, Poisoning are some of the diseases may be linked to SPR antibody. Blood, Bone, Brain, Eye, Heart, Kidney, Liver, Muscle, Skin, Vascular tissues are correlated with this protein.