anti-SPTBN1 antibody product blog
Tags: Antibody; Monoclonal Antibody; SPTBN1; Synuclein, alpha, beta; anti-SPTBN1 antibody;
The SPTBN1 sptbn1 (Catalog #MBS632095) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Synuclein, alpha, beta reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Synuclein, alpha, beta can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:1000-1:5000. Researchers should empirically determine the suitability of the SPTBN1 sptbn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SPTBN1 sptbn1 product has the following accession number(s) (GI #112382250) (NCBI Accession #NP_003119.2) (Uniprot Accession #Q01082). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
a-synuclein (amino acids 119-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. a-synuclein has been suggested to be implicated in the pathogenesis of Parkinson\'s disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Specially, the non-AB component of amyloid plaques is a highly amyloidogenic peptide consisting of 35 amino acids which was first identified associated with senile plaques in the Alzheimer\'s disease brain.
Immunogen: Recombinant human a-synuclein (119-140aa) (e. coli). Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SPTBN1 are readily searchable from our website. Different antibodies against the same target such as SPTBN1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Eye, Heart, Kidney, Lung, Muscle, Nerve, Placenta tissues are correlated with this protein. SPTBN1 also interacts with the following gene(s): ANK2, NF2, SPTAN1, SPTB. Brain Diseases, Carcinoma, Hepatocellular, Disease Models, Animal, Fractures, Bone, Inflammation, Liver Diseases, Neoplasms, Neoplasms, Experimental, Nervous System Diseases, Pancreatic Neoplasms are some of the diseases may be linked to Synuclein, alpha, beta.