anti-STX1A antibody product blog
Tags: Antibody; Monoclonal Antibody; STX1A; anti-STX1A antibody;
The STX1A stx1a (Catalog #MBS838380) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s STX1A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).WB: 1:1000
IHC: 1:100. Researchers should empirically determine the suitability of the STX1A stx1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The STX1A stx1a product has the following accession number(s) (GI #48146153) (NCBI Accession #CAG33299.1) (Uniprot Accession #Q75ME0). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the STX1A antibody with the following immunoassay(s):
Western Blot (WB) (Western blot of rat cortex lysate showing specific immunolabeling of ~ 36k syntaxin 1A protein)
Mouse monoclonal STX1A antibody.
Biological Significance: STX1A vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor which produces explosive exocytosis. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing STX1A are readily searchable from our website. Different antibodies against the same target such as STX1A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Cardiovascular Diseases, Cognition Disorders, Diabetes Mellitus, Disease Models, Animal, Fibrosis, Heart Diseases, Movement Disorders, Necrosis, Nerve Degeneration, Neurobehavioral Manifestations are some of the diseases may be linked to STX1A antibody. Brain, Embryonic Tissue, Eye, Ganglia, Kidney, Lung, Mouth, Muscle, Nerve, Pancreas tissues are correlated with this protein.