anti-Synaptopodin antibody product blog
Tags: Antibody; Synaptopodin; Monoclonal Antibody; anti-Synaptopodin antibody;
The Synaptopodin n/a (Catalog #MBS603623) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Synaptopodin (SYNPO, KIAA1029) reacts with Bovine, Guinea Pig, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Synaptopodin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry (frozen sections and paraffin-embedded tissue after microwave treatment): 1:5-1:10. Incubate for 1hr at RT. Researchers should empirically determine the suitability of the Synaptopodin n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Synaptopodin n/a product has the following accession number(s) (GI #33323347) (NCBI Accession #AAQ07403.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Synaptopodin, a prolin-rich actin-binding protein with 2 binding sites for actin, represents a new class of actin-binding proteins which has first been localized in podocytes and a subset of telencephalic postsynaptic densities. In human tissue synaptopodin has a molecular weight of 73.7kD and pI of 9.38 (calculated from sequence data); in mouse the corresponding data are 74kD, pI 9.27. In SDS-PAGE the antigen appears as 100kD polypeptide in brain and 110kD polypeptide in kidney (the difference might be attributed to posttranslational modifications).
Immunogen: Isolated rat kidney glomeruli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Synaptopodin are readily searchable from our website. Different antibodies against the same target such as Synaptopodin may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.