anti-SYP antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-SYP antibody; SYP;
The SYP syp (Catalog #MBS850939) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SYP Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s SYP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).WB: 1:500-1:2000
IHC: 1:200-1:1000
ELISA: 1:10000. Researchers should empirically determine the suitability of the SYP syp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SYP syp product has the following accession number(s) (GI #27764867) (NCBI Accession #NP_003170.1) (Uniprot Accession #P08247). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the SYP Antibody with the following immunoassay(s):
Western Blot (WB) (Figure 1: Western blot analysis using SYP mouse mAb against rat brain tissue lysate.)
Immunohistochemistry (IHC) (Figure 2: Immunohistochemical analysis of paraffin-embedded human Small Intestine, myenteric plexus tissues using anti-SYP mouse mAb)
Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex.
Immunogen: Purified recombinant fragment of SYP expressed in E. Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SYP are readily searchable from our website. Different antibodies against the same target such as SYP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. SYP also interacts with the following gene(s): GRB2, VAMP2. Blood, Brain, Embryonic Tissue, Eye, Intestine, Kidney, Lung, Nerve, Pineal Gland, Prostate tissues are correlated with this protein. Brain Diseases, Cardiovascular Diseases, Cognition Disorders, Disease Models, Animal, Drug Toxicity, Kidney Diseases, Liver Diseases, Memory Disorders, Nervous System Diseases, Neurobehavioral Manifestations are some of the diseases may be linked to SYP Antibody. The following patways have been known to be associated with this gene.