anti-T1/ST2 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-T1/ST2 antibody; T1/ST2; T1/ST2 (IL-33R);
The T1/ST2 n/a (Catalog #MBS442003) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s T1/ST2 (IL-33R) can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the T1/ST2 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Mouse T1/ST2 (IL-33 R) FITC conjugated monoclonal antibody (clone DJ8) for the identification and purification of murine T helper 2 (Th2) cells and all forms of murine mast cells.
Overview: T1/ST2 (also known as IL-1 R4 or IL-33Ra) is a transmembrane glycoprotein expressed on mast cells and Th2 cells. It is a selective marker for both murine and human Th2 lymphocytes and plays a role in regulating inflammatory responses. IL-33 is a recently identified member of the IL-1 family of cytokines and is involved in Th2 mediated immune responses. IL-33 mediates its biological effects via T1/ST2 binding. The roles of IL-33 and T1/ST2 (IL-33Ra) have been investigated in many immune responses such as allergy, asthma, rheumatoid arthritis and osteoarthritis.
Immunogen: Eukariotically expressed fusion protein of mouse T1 ectodomain and human immunoglobulin Fc domain. Data Specifications: Rat anti-Mouse T1/ST2 FITC-conjugated mAb
How To Use: This antibody allows the identification and purification of murine T helper 2 cells and all forms of murine mast cells.
Warning: This reagent contains 0.1% sodium azide as preservative. Due to potential hazards arising from the build up of this material in pipes, spent reagent should be disposed of with liberal volumes of water. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing T1/ST2 are readily searchable from our website. Different antibodies against the same target such as T1/ST2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.