anti-TAF15 antibody product blog
Tags: Antibody; Monoclonal Antibody; TAF15; anti-TAF15 antibody;
The TAF15 n/a (Catalog #MBS555044) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The TAF15, Monoclonal Antibody, Mouse reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TAF15 can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB). Researchers should empirically determine the suitability of the TAF15 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TAF15, Monoclonal Antibody, Mouse with the following immunoassay(s):
Testing Data (Image: shows HeLa cell cultures stained with TAF15 antibody (green) and chicken antibody to Vimentin (red). TAF15 reveals a granular nuclear localization typical of many RNA associated proteins. Blue is a DNA stain.)
Testing Data (Image: Blots of crude HeLa cell homogenate blotted with TAF15. The monoclonal antibody binds strongly and cleanly to a band at about 68 kDa.)
TAF15 is a member of a family of 3 closely related mammalian RNA binding proteins, the other members being FUS/TLS and EWSR1. TDP43 is a more distant relative of these three. The protein is also known as RBP56, for RNA binding protein 56kDa. As with the other members of this family, TAF15 contains one copy of the ~90 amino acid RRM domain. RRM is an acronym for RNA Recognition Motif, and this domain is found in many proteins which bind single stranded RNA and DNA. Like TDP43, Fus/TLS and EWS, TAF15 is widely expressed in tissues and is localized primarily in the nucleus of cells. It was recently shown that point mutations in TAF15 may be associated with some familial forms of Amyotrophic Lateral Sclerosis (ALS).
Type Info: Mouse IgG. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TAF15 are readily searchable from our website. Different antibodies against the same target such as TAF15 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.