anti-TBCC antibody product blog
Tags: Antibody; Monoclonal Antibody; TBCC; anti-TBCC antibody;
The TBCC tbcc (Catalog #MBS648557) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TBCC (Tubulin-specific Chaperone C, Tubulin-folding Cofactor C, CFC) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TBCC can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the TBCC tbcc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TBCC tbcc product has the following accession number(s) (GI #4507373) (NCBI Accession #NP_003183.1) (Uniprot Accession #Q15814). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MESVSCSAAA VRTGDMESQR DLSLVPERLQ RREQERQLEV ERRKQKRQNQ EVEKENSHFF VATFARERAA VEELLERAES VERLEEAASR LQGLQKLIND SVFFLAAYDL RQGQEALARL QAALAERRRG LQPKKRFAFK TRGKDAASST KVDAAPGIPP AVESIQDSPL PKKAEGDLGP SWVCGFSNLE SQVLEKRASE LHQRDVLLTE LSNCTVRLYG NPNTLRLTKA HSCKLLCGPV STSVFLEDCS DCVLAVACQQ LRIHSTKDTR IFLQVTSRAI VEDCSGIQFA PYTWSYPEID KDFESSGLDR SKNNWNDVDD FNWLARDMAS PNWSILPEEE RNIQWD.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TBCC (Tubulin-specific Chaperone C, Tubulin-folding Cofactor C, CFC) with the following immunoassay(s):
Testing Data (Detection limit for recombinant GST tagged TBCC is 0.3ng/ml as a capture antibody.)
Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors An and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
Immunogen: Full length recombinant corresponding to aa1-347 from human TBCC (AAH20170) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TBCC are readily searchable from our website. Different antibodies against the same target such as TBCC may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Retinal Degeneration are some of the diseases may be linked to TBCC (Tubulin-specific Chaperone C, Tubulin-folding Cofactor C, CFC).