|The TBP tbp (Catalog #MBS9200626) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TBP Antibody reacts with Human, mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s TBP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB).
WB~~1:1000. Researchers should empirically determine the suitability of the TBP tbp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TBP tbp product has the following accession number(s) (GI #285026520) (NCBI Accession #NP_001165556.1) (Uniprot Accession #P20226). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TBP Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded H. testis section using TBP Antibody. MBS9200626 was diluted at 1:25 dilution. An undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.)
Western Blot (WB) (TBP Antibody western blot analysis in Hela,HepG2,mouse NIH/3T3 cell line lysates (35ug/lane).This demonstrates the TBP antibody detected the TBP protein (arrow).)
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
Antigen Type: Recombinant Protein
Crown Antibody: Yes. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TBP are readily searchable from our website. Different antibodies against the same target such as TBP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. TBP also interacts with the following gene(s): GTF2B, TAF1, TAF10, TAF11, TAF12, TAF2, TAF4, TAF5, TAF6, TAF7. Blood, Bone, Brain, Heart, Kidney, Lung, Muscle, Nerve, Skin, Testis tissues are correlated with this protein.