|The TBX21 n/a (Catalog #MBS632922) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TBX21 (T-box Transcription Factor TBX21, T-box Protein 21, Transcription Factor TBLYM, T-cell-specific T-box Transcription Factor T-bet, TBET, TBLYM) (Azide Free) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TBX21 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:500-1:1000
ELISA: 1ug/ml-3ng/ml. Researchers should empirically determine the suitability of the TBX21 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TBX21 n/a product has the following accession number(s) (GI #7019549) (NCBI Accession #NP_037483.1) (Uniprot Accession #Q53EK5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Immunogen: Partial recombinant protein corresponding to aa387-486 of human TBX21 with a GST tag. The MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TBX21 are readily searchable from our website. Different antibodies against the same target such as TBX21 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Asthma, Brain Diseases, Disease Models, Animal, Hypersensitivity, Inflammation, Kidney Diseases, Lung Diseases, Necrosis, Neoplasms, Respiratory Hypersensitivity are some of the diseases may be linked to TBX21 (T-box Transcription Factor TBX21, T-box Protein 21, Transcription Factor TBLYM, T-cell-specific T-box Transcription Factor T-bet, TBET, TBLYM) (Azide Free).