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anti-TCR beta chain antibody product blog

Posted on 2016-04-06 06:12:28 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; TCR beta chain; anti-TCR beta chain antibody;
The TCR beta chain n/a (Catalog #MBS2534264) is an Antibody produced from Hamster and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse TCR beta chain Antibody (BIOT conjugated) reacts with Mouse and may cross-react with other species as described in the data sheet.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used <= 0.5 ug /106 cells in 100 ul). Since applications vary, the appropriate dilutions must be determined for individual use. Researchers should empirically determine the suitability of the TCR beta chain n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The TCR beta chain n/a product has the following accession number(s) (GI #339361) (NCBI Accession #AAA61095.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Mouse TCR beta chain Antibody (BIOT conjugated) with the following immunoassay(s):
Flow Cytometry (FC/FACS) (C57BL/6 mouse splenocytes stained with FITC anti-mouse CD3 and Biotin anti-mouse TCR ? chain, followed by PE-SA)
Flow Cytometry (FC/FACS) TCR beta chain.

T cell receptor (TCR) is a heterodimer consisting of an alpha and a beta chain (TCR alpha/beta) or a gamma and a delta chain (TCR gamma/delta). TCR-beta is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-alpha). It is expressed on alpha/beta TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.

Conjugation: BIOT. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TCR beta chain are readily searchable from our website. Different antibodies against the same target such as TCR beta chain may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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