|The TFIIH gtf2h1 (Catalog #MBS857759) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TFIIH (GTF2H1) Antibody reacts with Human, Mouse, Dog, Bovine, Pig, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s TFIIH can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the TFIIH gtf2h1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TFIIH gtf2h1 product has the following accession number(s) (GI #214831600) (NCBI Accession #NP_001135779.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TFIIH (GTF2H1) Antibody with the following immunoassay(s):
Testing Data (Western blot detection of TFIIH (N-terminus) in LNCAP&K562 cell lysates using TFIIH (N-terminus) antibody (1:1000 diluted). Predicted band size: 62KDa Observed band size: 62KDa.)
Testing Data #2 (Western blot detection of TFIIH(N-terminus)in Hela,Hela NE & Jurkat cell lysates using TFIIH (N-terminus) antibody (1:300 diluted).Predicted band size: 62KDa.Observed band size: 62KDa.)
Uniprot Summary: Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Immunogen: Purified recombinant human TFIIH protein fragments expressed in E.coli.
Cellular Localization: Nucleus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TFIIH are readily searchable from our website. Different antibodies against the same target such as TFIIH may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Carcinoma, Hepatocellular, Heart Diseases, Hyperglycemia, Inflammation, Kidney Diseases, Liver Diseases, Necrosis, Nervous System Diseases, Weight Loss are some of the diseases may be linked to TFIIH (GTF2H1) Antibody. Adipose Tissue, Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Muscle, Nerve tissues are correlated with this protein. TFIIH also interacts with the following gene(s): XPA, XPC. The following patways have been known to be associated with this gene.