anti-TG antibody product blog
Tags: Antibody; Thyroglobulin; Monoclonal Antibody; anti-TG antibody;
The TG tg (Catalog #MBS2542088) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TG Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TG can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).WB: 1:500-1:5000
IHC: 1:50-1:500. Researchers should empirically determine the suitability of the TG tg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TG tg product has the following accession number(s) (GI #55770862) (NCBI Accession #NP_003226.4) (Uniprot Accession #P01266). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TG Monoclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Transfected HEK-293 cells using Thyroglobulin Monoclonal Antibody at dilution of 1:1000)
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.
Immunogen: Fusion protein of Thyroglobulin. Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation: Unconjugated. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TG are readily searchable from our website. Different antibodies against the same target such as TG may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Brain Diseases, Carcinoma, Drug Toxicity, Fatty Liver, Hypertension, Inflammation, Liver Diseases, Necrosis, Thyroid Diseases, Thyroid Neoplasms are some of the diseases may be linked to TG Monoclonal Antibody. Blood, Brain, Connective Tissue, Intestine, Kidney, Liver, Lymph Node, Muscle, Pancreas, Thyroid tissues are correlated with this protein.