anti-TIAM antibody product blog
Tags: Antibody; Monoclonal Antibody; TIAM; anti-TIAM antibody;
The TIAM n/a (Catalog #MBS570259) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse anti TIAM reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TIAM can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) (frozen), Western Blot (WB).F5S F6.2 is useful for western blot and immunohistochemistry on frozen sections. Optimal antibody dilution should be determined by titRation. Researchers should empirically determine the suitability of the TIAM n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Tiam1, also known as T-cell lymphoma invasion and metastasis-inducing protein 1, is a protein that in Humans is encoded by the TIAM1 gene. TIAM1 is tightly associate with BAIAP2 as a subunit. It contains one DH (DBL-homology) domain, one PDZ domain, two PH domains and one Ras-binding RBD domain. TIAM1 modulates the activity of Rho GTP-binding proteins and connects extracellular signals to cytoskeletal activities. In addition, TIAM1 activates Rac1, CDC42, and to a lesser extent RhoA. TIAM1 is found in virtually all tumor cell lines examined including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.
Source Note: F5S F6.2 is a Mouse monoclonal IgG2b antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with T-cell lymphoma invasion and metastasis-inducing protein 1 (Tiam1). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TIAM are readily searchable from our website. Different antibodies against the same target such as TIAM may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.