anti-TNC antibody product blog
Tags: Antibody; TNC; Monoclonal Antibody; TENASCIN; anti-TNC antibody;
The TNC tnc (Catalog #MBS649247) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Tenascin, NT (Cytotactin, Tenascin C, Glioma associated Extracellular Matrix Antigen, GMEM, Hexabrachion) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Tenascin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in Immunohistochemistry and Western Blot. Researchers should empirically determine the suitability of the TNC tnc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TNC tnc product has the following accession number(s) (GI #153946395) (NCBI Accession #NP_002151.2) (Uniprot Accession #P24821). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Tenascin is a large glycoprotein that forms disulfide-linked hexamers. Tenascin is made up of a series of repeated structural domains including EGF-like repeats, fibronectin type III repeats, and a region homologous to fibrinogen. Splice variants of tenascin differ in their number of fibronectin type III repeats. Tenascin is expressed in distinctive spatial and temporal patterns in most embryonic tissues at sites of tissue remodeling and cell migration. There is little expression of tenascin in adult tissues except, again, at sites of tissue remodeling and cell migration such as surrounding tumors, in healing wounds, and in branching or damaged blood vessels.
Immunogen: Synthetic peptide to human Tenascin located in the N-terminal region. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TNC are readily searchable from our website. Different antibodies against the same target such as TNC may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. TNC also interacts with the following gene(s): SDC4, SRC. The following patways have been known to be associated with this gene. Bone, Brain, Connective Tissue, Embryonic Tissue, Liver, Lung, Muscle, Skin, Spinal Cord, Thymus tissues are correlated with this protein. Brain Diseases, Breast Neoplasms, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Heart Diseases, Inflammation, Necrosis, Neoplasms, Nervous System Diseases are some of the diseases may be linked to Tenascin, NT (Cytotactin, Tenascin C, Glioma associated Extracellular Matrix Antigen, GMEM, Hexabrachion).