anti-TNFRSF8� antibody product blog
Tags: Antibody; Monoclonal Antibody; TNFRSF8�; anti-TNFRSF8� antibody;
The TNFRSF8� tnfrsf8 (Catalog #MBS2544075) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human�TNFRSF8� Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TNFRSF8� can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA).ELISA: 0.1-0.2 mug/mL. This antibody can be used at 0.1-0.2 mug/mL with the appropriate secondary reagents to detect Human TNFRSF8. The detection limit for Human TNFRSF8 is approximately 0.00245 ng/well. Researchers should empirically determine the suitability of the TNFRSF8� tnfrsf8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TNFRSF8� tnfrsf8 product has the following accession number(s) (GI #597709795). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin\'s disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin\'s lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).
Immunogen: Recombinant Human CD30/TNFRSF8 protein
Buffer: 0.2 mum filtered solution in PBS with 5% trehalose. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TNFRSF8� are readily searchable from our website. Different antibodies against the same target such as TNFRSF8� may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Embryonic Tissue, Intestine, Lung, Lymph Node, Salivary Gland, Testis, Uterus tissues are correlated with this protein. TNFRSF8� also interacts with the following gene(s): ALK, CD4, CD5, FUT4, ICAM1, TNFSF8, TRAF1, TRAF2, TRAF3, TRAF5. The following patways have been known to be associated with this gene.